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Health Risks of Obesity

The medical importance of morbid obesity is that people who are very obese have higher rates of medical problems, translating into greater need for weight loss and the rationale for more extreme measures (such as bariatric surgery) to control the weight. The medical complications of obesity may occur in moderately obese people but the frequency of these associated problems increases dramatically as weight increases. For example, very obese men between the ages of 25 and 35 have 12-fold greater risk of dying prematurely compared to their normal weight counterparts.

Medical conditions that are commonly caused or exacerbated by obesity are considered “co-morbidities”. Below is a list of these medical conditions that are expected to resolve or improve after weight-loss surgery.

Pulmonary
The obese have decreased lung volumes and a decreased expiratory reserve volume causing obstructive sleep apnea, obesity hypoventilation syndrome, cor pulmonale and Asthma/Reactive Airway Disease.

Cardiac
High blood pressure is 6 times more prevalent in the obese person than in average weight people. The morbidly obese population has a 55-60% higher prevalence of hypertension. Increased weight at a young age is a risk factor for later development of hypertension.

The relationship of obesity to the incidence of Coronary Artery Heart Disease (CAHD) has been documented in a large number of studies. The Framingham Study is a large general population-based study with a long period of follow-up. Results indicate an increased risk of CAHD with increasing levels of obesity: for each 10% increase in body weight there is a 20% increase in the incidence of CAHD.

Gastrointestinal and Abdominal
There is a six times increase in incidence of gallstones (Cholelithiasis) in obese women between 20-30 years. At the age of 60, 33% of women will have gallbladder disease. Other problems include recurrent heartburn or GERD (Gastro esophageal Reflux Disease) and recurrent hernias.

Endocrine
Moderate obesity will increase the risk of Non-insulin dependent diabetes mellitus (NIDDM) or type II diabetes ten times and as a result, 33% of the morbidly obese have diabetes. Reducing weight in diabetics will improve glucose control, hypertension, heart attack, stroke, blindness and amputation.

Genitourinary, Reproductive
There is an increase of irregular menstruation in obese women leading to irregular periods and infertility. During pregnancy the obese can have an increase in toxemia and hypertension. Menses occurs earlier in obese girls. Frequent urinary track infections and stress urinary incontinence are other problems

Musculoskeletal
An increase in weight can cause degeneration or osteoarthritis of the spine, knees, and hips, and also creates more problems like disc herniation and chronic non-surgical low back pain. An increase in uric acid levels due to excess weight increases the prevalence for Gout. The joints are traumatized by increased weight demand but weight loss can relieve or decrease the chance of osteoarthritis.

Cancer Risk
Studies show a correlation between obesity and certain kinds of cancer. The American Cancer Society (ACS) Study involving more than 1 million men and women found that obese males had a higher mortality from cancer of the colon, rectum and prostate. Men who are 130% above average weight have a 2.5 times higher chance of death from prostate cancer in a 20-year follow-up study. Obese females had a higher mortality from cancer of the gallbladder, biliary tract, breast (postmenopausal), uterus (including both cervix and endometrium) and ovaries. In the case of endometrial cancer, women with marked obesity showed the highest relative risk (5.4) compared to non-obese.

Psychological Disorders
The obese person has difficulty in daily life, work, recreation, social interaction and sleep. Because of their limitations in lung capacity and mobility they become physically impaired and become a target for discrimination. They suffer from an impairment of their body image, which can lead to depression.

Here is a relative risk of a person with a BMI of 25 compared to a person with a BMI of 40:


    Disease
  • Death: All Causes
  • Death: Heart Disease
  • Death: Cancer
  • Type II Diabetes
  • High Blood Pressure
  • Stroke
    BMI=25
  • 1.1
  • 2.0
  • 1.1
  • 6.0
  • 1.1
  • 1.1
      BMI=40
  •   2.0
  •   6.0
  •   1.6
  • 53.0
  •   3.5
  •   2.0

 
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